Glutathione Dosage

Glutathione is a small protein that is naturally produced in plants and animals. In the human body, it is produced in the liver to help defend the body against toxic substances like free radicals, peroxides, and toxic metals. It also helps eliminate toxic chemicals like drugs and pollutants.

When there is low glutathione, there is an increased risk of developing health problems like cancer, type 2 diabetes, hepatitis, and Parkinson’s disease. Even though present in supplement form, you can support the body by helping it create more of this compound. Certain nutrients—like curcumin, selenium, vitamin C, and vitamin E—can assist the liver in producing more Glutathione. But, when that is not enough, you can always opt for man-made forms like Glutathione peptide.

Dosage Chart

What is Glutathione?

Glutathione is a highly effective antioxidant that is present in all the cells of the human body. It is made up of three amino acids, the building blocks that constitute proteins throughout the body.
The reason why glutathione is different from many other antioxidants is that the body can actually produce it for itself, mostly in the liver. This is something that most antioxidants cannot do.
Glutathione plays several key roles in the body, including:

• Help create DNA, necessary for protein and cell construction
• Support the immune system
• Neutralize toxic free radicals
• Support the function of some enzymes
• Restore vitamins C and E to their active forms
• Aid programmed cell death or apoptosis
• Aid the metabolism of fats by the liver and gallbladder

Low glutathione levels have been linked to various diseases. Increasing these levels has led people to seek oral or IV supplements.

Another way to boost glutathione is to use supplements that cause the body to produce more naturally. Some of these are milk thistle, N-acetylcysteine, and superoxide dismutase.
Lifestyle –especially staying away from toxins and eating a balanced diet—will also assist the body in keeping healthy glutathione levels.

Key Benefits of Glutathione

Glutathione is a vital antioxidant that delivers many health benefits. Some of the best researched ways in which it promotes health are listed below:

Reduces Oxidative Stress

Oxidation is a normal chemical process within the body, such as breathing, but too much oxidation destroys cells and tissues. Glutathione reverses this by acting as an antioxidant that cleans up free radical damage. If antioxidant levels go down and oxidants increase, then oxidative stress occurs. The body has to make more glutathione to fight it.

Protects Liver Cells

The liver is the key organ to detoxify chemicals and poisons and to metabolize nutrients. Glutathione, which is made in the liver, guards liver cells against oxidative damage caused by environmental toxins or medicines. In laboratory tests, animals with low glutathione levels showed symptoms of liver problems. Human research also found that both IV and glutathione improved health in people with chronic liver disease.

Regulates Blood Sugar Levels

Diabetes is both related to insulin resistance and elevated blood glucose, and both of these have the ability to increase oxidative stress. Decreased glutathione levels have been observed in diabetics. Supplementing those nutrients that raise glutathione levels can reduce oxidative damage and enhance insulin response.

Eases Parkison’s Disease Symptoms

Parkison’s is a disease affecting the brain cells and motor function. Research suggests that individuals with this disease have compromised levels of glutathione in their brains. Some clinical trials say that supplementing glutathione will enhance movement and slow disease progression.

Aids in Controlling Ulcerative Colitis

Oxidative stress also plays a role in gut inflammation, such as ulcerative colitis. Patients with this disease have lower levels of antioxidants before symptoms, and increasing glutathione may help defend against intestinal cell damage and further injury.

May Lower Autoimmune Risk

In autoimmune diseases, healthy tissue is targeted by the immune system, resulting in inflammation and oxidative stress. Glutathione controls immune processes and opposes inflammation. Increased glutathione can help in diseases like lupus, multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.

Improves Cellular Functions

Glutathione plays a function in critical processes including gene expression and DNA synthesis. It will dictate how cells repair themselves, make proteins, and respond to changes within. The functions are there to ensure the health of the cells and overall body function.

May Benefit Skin Conditions such as Psoriasis

Studies indicate that raising the level of glutathione with the assistance of whey protein intake may improve psoriasis. Although promising, research is needed to confirm its effectiveness.

Assists Cystic Fibrosis Management

This inherited condition affects the lungs and the gastrointestinal system. Glutathione may help reduce inflammation of the lungs as well as assist in child growth and nutrition for cystic fibrosis. Long-term benefits, however, need further studies.

Improves Peripheral Artery Disease Circulation

Peripheral artery disease reduces blood supply to the legs. Glutathione has been shown to increase walking distance without pain in patients by improving circulation and reducing oxidative damage.

May Be of Benefit with Autism Spectrum Disorders

Autistic children have lower glutathione levels, and this has been linked to oxidative stress in the brain. Transdermal and oral glutathione has had some trials showing it increases antioxidant levels, which may help decrease symptoms.

Slows Signs of Aging

When a person becomes older, the body makes less glutathione, leaving cells vulnerable to damage. Glutathione supplements have been linked by studies to more radiant skin tone, elasticity, and lower signs of aging like wrinkles.

Helps with Nutrient Metabolism

Glutathione assists in breaking down and metabolizing nutrients, especially vitamins like C and E. It is part of the process of converting food into energy as well as maintaining proper nutritional balance within the body.

Increases Athletic Performance

Extreme exercise increases oxidative molecules, leading to muscle fatigue. Glutathione, through increasing its concentration, allows the muscles to handle oxidative stress better, perhaps increasing endurance and reducing fatigue.

Glutathione Dosage

Now that you know what Glutathione is and how it works, you need to adjust the right dose. When it comes to dosing, it will mostly depend on what you are taking it for. Several studies indicate positive results with dosage between 250-300mg daily, but in some cases, high doses might be required.
In one study, scientists found that 300mg per day of Glutathione for 16 weeks improved liver function and health in people with non-alcoholic fatty liver, while another study showed that taking 250mg of this peptide daily was great for aging and skin health.

Based on recent studies, how much you take may translate to individual cases, but it seems that 250mg could be the dosage that works for the majority of patients.

Scientists confirm that the most effective form of administration is through daily or weekly injections, For weekly injections dosing will be higher (600mg-1200mg of the peptide, once or twice a week).

Conclusion

As one of the crucial elements in the body, Glutathione levels are crucial to maintaining good health. Scientists have managed to associate low levels of this peptide with several medical conditions. While supplementation might be appropriate for some people, it might not be safe for everyone, as it could interact with other medications.
Before you start with Glutathione, make sure to consult your doctor, to avoid any potential side effects.