Prostamax Dosage

Prostamax is a synthetic peptide from the Khavinson peptide family, consisting of four amino acids. Its primary use is related to prostate tissue repair, which can be used in treating conditions such as acute prostatitis, age-related prostatic symptoms, or reduced urine flow through the urinary tract. Additionally, this peptide exhibits anti-aging properties, making it crucial for the development of aesthetic and regenerative medicine. Anti-inflammatory properties, improved immunity, and enhanced cellular profile in the pediatric population are just some of the benefits this molecule provides. Some research suggests that the peptide may be used as an antineoplastic compound in treating certain cancers. This property remains unexplored but is currently the subject of ongoing study.

Dosage Chart

About the Peptide

Prostamax is a synthetic peptide from the Khavinson peptide family, composed of four amino acids. This amino acid sequence is most expressed in prostate tissue, where its primary effects and results have been found. Scientists assume that the peptide achieves most of its functions by modifying the expression of DNA molecules.

Its primary function is based on the repair of prostate tissue, treating acute and chronic conditions, symptoms related to reduced urinary tract flow, and the improvement of the overall condition of patients suffering from age-related prostate conditions.

The prostate is a small gland located just below the bladder and belongs to the male reproductive system. It is responsible for producing the central part of semen (the liquid component without sperm) and regulating ejaculation. Many pathological conditions can affect this tissue, resulting in severe symptoms. Most of them are associated with men over the age of fifty who are at risk. Some of the crucial prostate diseases include acute and chronic prostatitis, prostate cancer, benign prostatic hyperplasia, or just symptoms related to an obstructed urinary tract that have not yet found their official diagnosis.

Based on scientific research, Prostamax can reduce swelling and the number of scars on the prostate (preventing further tissue remodeling). Patients who suffer from acute conditions for a long time can eventually develop a chronic process, hypertrophy, hyperplasia, and, in the worst case, cancer. It has been found that therapy with this peptide can significantly reduce the risk of serious consequences.

Another beneficial property of the peptide is its anti-inflammatory effect on prostate tissue, as well as other cells. Scientific studies have shown that this effect is achieved by stimulating the ribosomes of lymphocytes, which are primarily responsible for immune response. It thus enhances the health of lymph nodes and increases gene expression at all levels. This effect essentially works to reduce inflammatory reactions, the spread of infection, and the progression of the disease into hyperplasia and cancer. Normalization of cell growth and differentiation are the key benefits brought by the anti-inflammatory effect.

In the aging process, DNA condensation is a physiologically normal process that contributes to visible signs of aging in both men and women. With its heterochromatin decondensation effect, Prostamax has an anti-aging effect, reducing those signs. The results of therapy with this peptide include reduced apoptosis and increased cell proliferation, along with improved expression of protein molecules.

List of Uses

Influence on the Development of Inflammatory Processes in the Prostate

Prostatitis is an acute or chronic inflammation of the prostate gland, often present in men over fifty years of age, but it is also possible in young people. There is swelling of the gland, hyperemia (an increase in blood supply to the tissue), and lymphoid infiltration. Symptoms that the patient feels are burning and pain during urination or even the complete inability to urinate. Pain in the abdomen and lower back, urination at night accompanied by pus, fatigue, or increased body temperature are some of the common symptoms experienced by these patients. Such a condition can eventually lead to hypertrophy, hyperplasia, and even prostate cancer. Therapy in the form of antibiotics is often not completely effective, so research into Prostamax has personal value.

It has been observed that Prostamax reduces swelling and scarring of the gland after just a few days. This indicates the peptide's ability to limit remodeling and thereby prevent the spread of infection and progression to hyperplasia and cancer. It is considered that a special form of chronic abacterial prostatitis (CAP) is particularly challenging to treat because it lacks a bacterial etiology, making antibiotic therapy ineffective. However, it has been observed that this peptide also acts on this form of prostatitis, causing significant improvement in the condition and reduction of symptoms. Based on its mechanism of action, the peptide has been found to reduce all the primary signs of inflammation, including hyperemia, increased temperature, pain, and swelling. The results of studies on animals and humans have shown reduced swelling, cessation of pain, and reduced infiltration of blood and lymphatic vessels after starting therapy.

Anti-inflammatory Effect

This bioregulatory peptide may affect immunity by causing increased expression of ribosomes, which are responsible for protein synthesis and are found in lymphocytes. By opening the packed chromatin, the peptide exerts an anti-inflammatory effect that can significantly reduce the inflammation process and disease progression.

Gene expression is achieved at multiple levels, which substantially enhances the health and function of lymphocytes, thereby improving immunity. Scientific studies on humans have shown that short-term administration of peptides reduces the underlying signs of inflammation, thereby improving symptoms such as nighttime urination, painful urination, back pain, difficulty urinating, or the presence of pus in the urine.

For example, one of the main symptoms of prostatitis is delayed urination, which primarily occurs because the urethra passes through the prostate, so when it comes to swelling, its lumen is surrounded by swollen tissue, so urine cannot pass through such a tearful lumen. When the swelling decreases, and the inflammation subsides, urination continues normally.

Anti – Aging Effect

Scientists have discovered through research that Prostamax can affect DNA structure, decondensing heterochromatin. This allows for the expression of DNA molecules and their additional activation. This effect is crucial because chromatin condensation is an unintended but normal process that occurs throughout life and leads to visible aging processes, such as muscle atrophy, the appearance of wrinkles, and more. Those signs are the result of initial apoptosis, but the peptide can provide a younger genetic profile to cells, leading to enhanced protein production and improved cell function. Due to these effects, it is believed that this amino acid sequence can significantly aid the development of aesthetic and regenerative medicine, slowing down the aging process.

Dosage Calculator

The correct dosage, as always, depends on the indication. Prostamax (Bioregulator) is also used to treat prostatitis and other inflammatory conditions of the prostate, which determines the dosage protocol. According to scientific research and clinical studies, the optimal dose during the first 4 weeks is 0.75 mg, administered as a single subcutaneous injection daily. This treatment can last up to eight weeks, depending on the doctor's recommendations. According to studies to date, the maximum dose is 2 mg and is administered for 4 to 8 weeks. The maximum recommended dose should never be exceeded or changed independently to avoid side effects.

Conclusion

Prostamax is a potential peptide from the Khavinson family. It is primarily used to treat inflammatory processes in the prostate tissue, including acute and chronic prostatitis. Additionally, it exhibits beneficial effects, including reducing inflammation and possessing anti-aging properties. When used in an optimal dose and under the guidance of a doctor, this peptide can be a crucial part of treating diseases of the male reproductive system. Regardless of the achievements so far, Prostamax will undoubtedly continue to be the subject of research.

References:

1. Meskhi T, Khachidze D, Barbakadze Sh, Madzhagaladze G, Gorgoshidze M, Monaselidze D, Lezhava T, Tadumadze N. Vliianie peptidnogo bioreguliatora prostamaksa na geterokhromatin limfotsitov cheloveka in situ [The influence of the peptide bioregulator prostamax on heterochromatin of human lymphocytes in situ]. Biofizika. 2004 Nov-Dec;49(6):1091-3. Russian. PMID: 15612551.
2. Dzhokhadze TA, Buadze TZh, Gaĭozishvili MN, Baratashvili NA, Lezhava TA. [Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro)]. Georgian Med News. 2012 Nov;(212):76-82. Russian. PMID: 23221144.
3. Khavinson VK, Kormilets DY, Mar'yanovich AT. Peptides (Epigenetic Regulators) in the Structure of Rodents with a Long and Short Lifespan. Bull Exp Biol Med. 2017 Sep;163(5):671-676. doi: 10.1007/s10517-017-3876-x. Epub 2017 Sep 25. PMID: 28948547.
4. Zakutskiĭ AN, Chalisova NI, Ryzhak GA, Aniskina AI, Filippov SV, Zeziulin PN. [The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats]. Adv Gerontol. 2006;19:93-6. Russian. PMID: 17152728.
5. Borovskaya, T. G., Pakhomova, A. V., Vychuzhanina, A. V., Poluektova, M. E., Fomina, T. I., Ermolaeva, L. A., ... & Neplochov, E. A. (2013). Experimental studying of the drug efficiency Prostamax in the therapy of chronic aseptic prostatitis and its complications. Modern Research in Inflammation, 2013.